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ea0034p226 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2014

Meal size and frequency influences metabolic endotoxaemia and inflammatory risk but has no effect on diet induced thermogenesis in either lean or obese subjects

Piya Milan , Reddy Narendra , Campbell Alison , Hattersley John , Halder Louise , Tripathi Gyanendra , Tahrani Abd , Barber Thomas , Kumar Sudhesh , McTernan Philip

Background: Small frequent meals are often recommended for weight loss, with supporting evidence often provided from studies in diabetes. Dietary meal content is also relevant, as high fat meals cause systemic inflammation via gut derived bacteria, endotoxin. As such, repeated meals may exacerbate this. In contrast, dietary induced thermogenesis, related to meal size, may reduce with small frequent meals.Aim: Therefore, the aim of this study was to compa...

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ea0031p219 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013

Eating more quickly heightens overall systemic exposure to glucose and NEFA in the post-prandial phase, irrespective of energy expenditure in obese women

Reddy Narendra , Peng Chen , Piya Milan K , Aftab Saboor A S , Campbell Alison , Hattersley John , Halder Louise , Harte Alison L , Randeva Harpal , Tripathi Gyanendra , McTernan Philip G , Kumar Sudhesh , Barber Thomas M

Background/aim: The global obesity epidemic has promoted a search for novel solutions. One approach is through modification of eating-related behaviours. Our aim was to explore the effects of meal duration on energy expenditure, appetite and excursions of molecules associated with insulin sensitivity in the post-prandial phase.Methods: Normoglycaemic, pre-menopausal, Caucasian obese women (n=8) were recruited from the Obesity clinic at Warwicksh...

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Endocrine Abstracts

Meal size and frequency influences metabolic endotoxaemia and inflammatory risk but has no effect on diet induced thermogenesis in either lean or obese subjects

Eating more quickly heightens overall systemic exposure to glucose and NEFA in the post-prandial phase, irrespective of energy expenditure in obese women

BiosciAbstracts